Input Sequence

Paste your sequence:

or upload a local file in FASTA format:

Structural Constraints

Number of strands: minimum maximum
Strand length: minimum maximum
Periplasmic loop length: minimum maximum
Extra-cellular loop length: minimum maximum
Shear Number: minimum maximum

Maximum length variation between strands:

Enforce: Sum of membrane-facing barrel residues tends Hydrophobic
Sum of channel-facing barrel residues tends Hydrophillic
Sum of all barrel residues per strand tends Hydrophobic
Loops tend to be polar
Intracellular N-terminus

Scoring Function

Hydrophobic scale:
Polarity scale:
Contact potential:
Log(Z) estimate: Channel-facing residues: Membrane-facing residues:
Boltzmann & Temperature constant (RT):

Job Control

Find only the Minimum Folding Energy (MFE) structure (No ensemble calculations!)

Number of structures to sample from ensemble according to Boltzmann distribution

Email address of submitter (optional)